XDel Knockout Cells
Leveraging an innovative guide RNA design strategy, XDel Knockout Cell Pools and Clones deliver highly efficient, consistent, and reproducible loss of gene function.
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Reimagine Genome Engineering
Customized CRISPR solutions to fit your research needs: Choose from do-it-yourself CRISPR options or CRISPR done for you.
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Industrialized CRISPR Cells: CRISPR Done for You
EditCo's next-generation engineered cells provide researchers with access to the benefits of CRISPR. You no longer need to invest significant time and money to learn and optimize methods.
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Target Discovery: The Path to Screening with Confidence
EditCo offers CRISPR solutions from start-to-finish in your loss-of-function screening pipeline for more accurate, productive, and reproducible results.
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Arrayed CRISPR gRNA Libraries Quick Start Guide
EditCo’s human and mouse screening libraries utilize multi-guide gRNA that has been strategically designed to knock out your human or mouse protein-coding gene of interest. This quick-start guide provides instructions on how to prepare, use, store and quantify your gRNA library.
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Engineered T cells Quick Start Guide
This quick start guide can be used for our CD4+ and CD8+ Knockout T Cell Pools. In this guide, we include important information on how to store, resuscitate, and evaluate your cells. For additional details about your order, please refer to the corresponding QC Report.
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Engineered Cells–Milestone Definitions
There are many milestones that a cell line will pass through while on the EditCo platform. In this file you can find detailed information of the work that is performed in each milestone of an Engineered Cells order.
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CRISPR Editing of Human iPS Cells with RNPs Using Nucleofection
This protocol describes how to deliver ribonucleoprotein (RNP) complexes that consist of purified Cas9 nuclease duplexed with chemically modified synthetic single guide RNA (sgRNA) to induced pluripotent stem (iPS) cells derived from human fibroblasts.
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Arrayed CRISPR Multi-guide Library Nucleofection Using RNPs in Immortalized Cell Lines
This protocol describes how to deliver ribonucleoprotein (RNP) complexes that consist of purified Cas9 nuclease duplexed with chemically modified synthetic single guide RNA (sgRNA) to immortalized adherent or suspension cells.
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CRISPR Arrayed Multi-Guide Library Lipofection using Cas9-Expressing Cells
This protocol describes a high-throughput library lipofection method using Cas9-expressing cells.
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CRISPR Editing of Immortalized Cell Lines with RNPs using Nucleofection
This protocol describes how to deliver ribonucleoprotein (RNP) complexes that consist of purified Cas9 nuclease duplexed with chemically modified synthetic single guide RNA (sgRNA) to immortalized adherent or suspension cells.
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CRISPR Editing of Immortalized Cell Lines with RNPs using Neon Electroporation
This protocol describes how to deliver ribonucleoprotein (RNP) complexes that consist of purified Cas9 nuclease duplexed with chemically modified synthetic single guide RNA (sgRNA) to immortalized adherent or suspension cells.
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CRISPR Editing of Immortalized Cell Lines with RNPs Using Lipofection for 24-well Plates
This protocol describes how to deliver ribonucleoprotein (RNP) complexes that consist of purified Cas9 nuclease duplexed with chemically modified synthetic single guide RNA (sgRNA) to standard immortalized cell lines (adherent or suspension).
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Knockout CD8+ T-cell Pools
Edited-to-order Knockout CD8+ T-cells guarantee high knockout efficiency while retaining high cell viability and post-editing functionality.
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Knockout Primary Immune Cell Pools
Edited-to-order Knockout CD4+ T-cells guarantee high knockout efficiency while retaining high cell viability and post-editing functionality.
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CRISPR-Edited iPS Cells, Guaranteed
We offer knockouts, single nucleotide variants, and tag insertions in control or patient-derived iPS cell lines—available in homozygous or heterozygous clone or pool formats.
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Gene Knockout Kit: Elevate Your Guide Design Strategy
EditCo's Gene Knockout Kit takes the trial and error out of CRISPR knockouts by using a novel strategy of guide RNA design to knock out any human or mouse protein-coding gene.
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Engineered iPS Cell Quick Start Guide
This quick start guide can be used for both our Knockout and Knock-in iPS cells. In this guide, we include important information on how to store, resuscitate, and evaluate your cells. For additional details about your order, please refer to the corresponding QC Report.
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EditCo-Supplied PGP1 iPS Cell Line
This datasheet contains data confirming the genetic stability, pluripotency, and purity of the PGP1 iPS cell line, as well as quality control assessments for individual orders.
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Gene Knockout Kit Quick Start Guide
This quick start guide can be used for EditCo's Gene Knockout Kit. In this guide, we include important information on how to store, quantify, and transfect your gRNA kit and analyze your knockout kit experiments.
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EditCo-Supplied 802-30F iPS Cell Line
This datasheet contains data confirming the genetic stability, pluripotency, and purity of the 802-30F iPS cell line, as well as quality control assessments for individual orders.
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Cell Engineering 101 eBook
Discover methods and insights into skillfully generating knockout or knock-in CRISPR edits in a wide-range of cell lines.
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CRISPR-Engineered Cells Enable Variant Disease Modeling
Understand how all researchers can leverage CRISPR-engineered cells to model multiple genetic variants and clones at scale.
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Multi-guide RNA Improves CRISPR Efficiency by Generating Fragment Deletions
Learn how intelligently designed multiple gRNAs improve CRISPR knockout efficiency with single exon fragment deletions.
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Unlocking the Genetic Code: The Power of CRISPR in Modern Science
A comprehensive overview of CRISPR technology including its historical development, mechanisms, wide-ranging applications, and potential for changing the future of science.
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AI-driven identification and validation of novel synthetic lethal gene pairs through deep mining of cancer dependency data
Evariste have performed in silico modelling of cancer dependency data to identify the next generation of druggable synthetic lethal gene pairs. We have prioritised gene pairs with a rational mechanism linking the target and biomarker, and with patient populations with high levels of unmet need.
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High Quality On-Demand Gene Edited Human Primary T-cells
EditCo can quickly provide made-to-order edited T-cells from a variety of prevalidated donors. Edited T-cells retain their biologically relevant activation responses after thawing and expansion.
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Engineered Cells QC Report User Guide
In this document, we include information on how to interpret the information included in your QC document.
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Genotyping Protocol
After you have performed a CRISPR experiment, you can evaluate the genotype of the edited cells with either Next Generation Sequencing (NGS) or Sanger sequencing.
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CRISPR Screening 101
Learn how EditCo’s advanced screening libraries, featuring multi-guide technology and arrayed formats, can enhance your research and streamline your drug discovery process.
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Precision CRISPR Editing of Induced Pluripotent Stem (iPS) Cells
Explore how EditCo Bio's optimized protocols deliver knockout efficiencies of ~90% in iPS cell pools, all while guaranteeing your desired edits.
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Rapid and Efficient Genome Editing for Human Primary T-Cells
EditCo can quickly provide made-to-order edited T-cells from a variety of prevalidated donors. Edited T-cells retain their biologically relevant activation responses after thawing and expansion.
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Engineered Immortalized Cell Quick Start Guide
This quick start guide can be used for both our Knockout and Knock-in immortalized cell lines. In this guide, we include important information on how to store, resuscitate, and evaluate your cells. For additional details about your order, please refer to the corresponding QC Report.
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Advancing Gene Editing with Precision and Automation
Discover how EditCo's adoption of SPT Labtech’s comPOUND® system optimizes gene editing workflows and accelerates scientific discovery.
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Industrialized CRISPR iPS Cells Enable NIH Large Scale Alzheimer’s Disease Research Effort
Learn how EditCo's partnership with the NIH on the iPSC Neurodegenerative Disease Initiative (iNDI) project advances Alzheimer’s disease research.
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Automating Away Complexity: High-Throughput NGS Screening of CRISPR Edits
EditCo automated NGS library preparation workcell and its adjoining software are built to handle a huge array of CRISPR edits reliably every time within unique constraints. Our automation, software logic, analysis pipeline, and ability to deliver in time are best in class, allowing us to process thousands of samples a week and partner with industry leaders to help drive genetic disease research.
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Accelerating Gene-Editing Workflows Using an Integrated and Automated Platform for Managing Inventory and Delivery of Guide RNAs
EditCo’s unique multi-guide designs are available at unparalleled speeds through a robust automated inventory management and fulfillment platform. Specifications are defined and periodically checked to ensure that process-critical instruments are performing within expectations and the health of the process is monitored.
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