Product Guarantees
Learn about our commitment to your satisfaction.
Our Commitment to You
Engineered Immortalized Cells
XDel Cell Pools
EditCo guarantees* the delivery of gene-edited XDel Cell Pools with consistently high editing efficiency (target ≥90%), verified by NGS genotyping QC.
NGS genotyping QC data is included with each knockout immortalized cell pool. If internal NGS genotyping QC does not meet this performance threshold, EditCo will apply a discount to the order.
*EditCo guarantee does not apply if the edited gene in your knockout cell pool is deemed as Common Essential, per the DepMap Database.
Knockout Immortalized Cell Clone
EditCo guarantees the delivery of gene-edited knockout immortalized cell clones with consistently high editing efficiency (target 100%), verified by NGS genotyping QC.
NGS genotyping QC data is included with each Knockout Immortalized Cell clone. If internal NGS genotyping QC does not meet this performance threshold where a homozygous clone is ordered, EditCo will apply a discount to the order. Heterozygous Knockout Immortalized Cell Clones are not included in our guarantees.
EditCo guarantees do not apply if the edited gene in your knockout cell clone is deemed as Common Essential, per the DepMap Database. If you choose to continue with a gene that is identified as common essential, you will be invoiced for the full amount quoted upon completion of Milestone 1b (transfection and genotyping of the pool), regardless of whether clones are successfully isolated and with no guarantee of minimum editing efficiency. If a common essential gene is able to be knocked out successfully and created into a clone, we will continue with our process and invoice the full amount quoted.
Delivery of your Knockout Immortalized Cell Clones is dependent on the ability of the cell line to be isolated and grown from a single cell. In the event that the biology of the desired cell line prevents it from being clonally isolated and expanded and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 2) the option to cancel the project and utilize the funds for a new clonal project.
If we are unable to identify any clones of the zygosity specified on the quote and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of cell clones of an alternate zygosity at 75% of the quoted price 2) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 3) the option to cancel the project and utilize the funds for a new clonal project.
Knock-in Immortalized Cell Pool
Knock-In Immortalized Cell Pools are guaranteed to have detectable levels of the knock-In sequence at the specified target locus as confirmed by Next Generation Sequencing (NGS), Sanger sequencing or fragment PCR in our hands. Given the low frequency of knock-In repair, we are unable to guarantee a minimum knock-In percentage.
EditCo does not test protein levels or perform functional validation of the Knock-In Immortalized Cell Pools delivered.The genetic modifications confirmation should be conducted by the recipient within the first 7 days after thawing the Knock-In Immortalized Cell Pool. If, upon testing via genomic methods (e.g., Sanger sequencing), you cannot confirm the genetic modifications made, EditCo will apply a discount to the order.
Knock-in Immortalized Cell Clone
EditCo does not test protein levels or perform functional validation of the Knock-In Immortalized Cell Clones delivered. The genetic modifications confirmation should be conducted by the recipient within the first 7 days after thawing the Knock-In Immortalized Cell Clone. If, upon testing via genomic methods (e.g., Sanger sequencing), you cannot confirm the genetic modifications made, EditCo will apply a discount to the order. Products need to be tested as described above within 60 days of delivery.
Delivery of your Knock-In Immortalized Cell Clones is dependent on the ability of the cell line to be isolated and grown from a single cell. In the event that the biology of the desired cell line prevents it from being clonally isolated and expanded and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 2) the option to cancel the project and utilize the funds for a new clonal project.
If we are unable to identify any clones of the zygosity specified on the quote and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of cell clones of an alternate zygosity at 75% of the quoted price 2) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 3) the option to cancel the project and utilize the funds for a new clonal project.
Engineered iPS Cells
Knockout iPS XDel Cell Pool
EditCo guarantees* the delivery of gene-edited iPS XDel Cell Pools with consistently high editing efficiency (target ≥90%), verified by NGS genotyping QC.
NGS genotyping QC data is included with each Knockout iPS XDel Cell Pool.If internal NGS genotyping QC does not meet this performance threshold, EditCo will apply a discount to the order. Heterozygous Knockout iPS Cell Pools are not included in our guarantees.
*EditCo guarantee does not apply if the edited gene in your knockout cell pool is deemed as Common Essential, per the DepMap Database.
Knockout iPS Cell Clone
EditCo guarantees the delivery of gene-edited iPS Cell Clones with consistently high editing efficiency (target 100%), verified by NGS genotyping QC.
NGS genotyping QC data is included with each Knockout iPS Cell Clone. If internal NGS genotyping QC does not meet this performance threshold where a homozygous clone is ordered, EditCo will apply a discount to the order. Heterozygous Knockout Immortalized Cell Clones are not included in our guarantees. Heterozygous Knockout iPS Cell Clones are not included in our guarantees.
EditCo guarantees do not apply if the edited gene in your knockout cell clone is deemed as Common Essential, per the DepMap Database. If you choose to continue with a gene that is identified as common essential, you will be invoiced for the full amount quoted upon completion of Milestone 1b (transfection and genotyping of the pool), regardless of whether clones are successfully isolated and with no guarantee of minimum editing efficiency. If a common essential gene is able to be knocked out successfully and created into a clone, we will continue with our process and invoice the full amount quoted.
Delivery of your Knockout iPS Cell Clones is dependent on the ability of the cell line to be isolated and grown from a single cell. In the event that the biology of the desired cell line prevents it from being clonally isolated and expanded and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 2) the option to cancel the project and utilize the funds for a new clonal project.
If we are unable to identify any clones of the zygosity specified on the quote and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of cell clones of an alternate zygosity at 75% of the quoted price 2) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 3) the option to cancel the project and utilize the funds for a new clonal project.
Knock-in iPS Cell Pool
Knock-In iPS Cell Pools are guaranteed to have detectable levels of the knock-In sequence at the specified target locus as confirmed by Next Generation Sequencing (NGS), Sanger sequencing or fragment PCR in our hands. Given the low frequency of knock-In repair, we are unable to guarantee a minimum knock-In percentage.
EditCo does not test protein levels or perform functional validation of Knock-In iPS Cell Pools delivered. The genetic modifications confirmation should be conducted by the recipient within the first 7 days after thawing the Knock-In iPS Cell Pool. If, upon testing via genomic methods (e.g., Sanger sequencing), you cannot confirm the genetic modifications made, EditCo will apply a discount to the order. Products need to be tested as described above within 60 days of delivery.
Knock-in iPS Cell Clone
EditCo does not test protein levels or perform functional validation of Knock-In iPS Cell Clones delivered. The genetic modification confirmation should be conducted by the recipient within the first 7 days after thawing the Knock-In iPS Cell Clone. If, upon testing via genomic methods (e.g., Sanger sequencing), you cannot confirm the genetic modifications made, EditCo will apply a discount to the order. Products need to be tested as described above within 60 days of delivery.
Delivery of your Knock-In iPS Cell Clones is dependent on the ability of the cell line to be isolated and grown from a single cell. In the event that the biology of the desired cell line prevents it from being clonally isolated and expanded and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 2) the option to cancel the project and utilize the funds for a new clonal project.
If we are unable to identify any clones of the zygosity specified on the quote and the project is not subject to milestone-based payment terms, EditCo will offer 1) the option of delivery of cell clones of an alternate zygosity at 75% of the quoted price 2) the option of delivery of the cell pool for the same gene modification in the same cell line for the price of the pool or 3) the option to cancel the project and utilize the funds for a new clonal project.
Engineered Cell Libraries
EditCo guarantees that the Engineered Cell Library will have 70% of pools successfully analyzed by Sanger sequencing and ICE per plate (batch). 70% of successfully analyzed pools will have an indel frequency ≥50% per plate (batch). If an ECL product doesn’t meet the minimum QC criteria and there are no special payment stipulations, the customer will have the option of canceling the order or accepting the Engineered Cell Library at a reduced rate. We do not commit to re-work attempts in the quote terms.
Each tube will contain at least ~20,000 cells with the exception of Common Essential, per the DepMap Database and iPSC and immortalized cells derived from primary cells. If an ECL product doesn’t meet the minimum cell quantity requirement the following discount will be applied: 50% discount of the pool if one or more tubes contains <20,000 cells per tube. Pool free of charge if one of the tubes contains <10,000 cells per tube.
Product needs to be tested within 60 days of delivery.
User-Supplied Cells
Acceptance of user-supplied cells is dependent on the cells passing our stringent quality control tests in addition to their ability to thrive under our culture conditions. Customers will be asked to provide relevant culture conditions that will be used internally. If a cell line fails our quality control, we will contact you with the relevant information and allow you to send another batch of cells. If a cell line fails to thrive in our laboratory, we will contact you to confirm culture conditions and if necessary, arrange for a new cell line.
Engineered Primary Cells
Knockout Primary T cells
EditCo guarantees* the delivery of gene-edited Knockout Primary T Cell Pools with consistently high editing efficiency (target ≥90%), verified by NGS genotyping QC. NGS genotyping QC data is included with each Knockout Primary T Cell Pool.If internal NGS genotyping QC does not meet this performance threshold, EditCo will apply a discount to the order.
*EditCo guarantee does not apply if the edited gene in your knockout cell pool is deemed as Common Essential, per the DepMap Database.