Rapid, Reliable Knockouts for Cancer Biology with XDel Technology: Unveiling SURF2’s Role in Nucleolar Stress and Its Potential as a Therapeutic Target

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Understanding how cancer cells resist nucleolar stress is critical for developing more effective therapies. Dr. Simon Lebaron and his team at the Université de Toulouse identified SURF2 as a key regulator in this process—offering new insights into potential cancer treatments.

To move their research forward without the challenges of CRISPR optimization, the team used EditCo’s XDel Knockout Cells, enabling them to quickly generate robust and permanent SURF2 knockout models. This allowed them to focus on characterizing the impact of SURF2 on nucleolar stress and tumor progression, rather than spending valuable time creating knockout cell lines.

Download the case study to learn how CRISPR knockout models streamlined their research and uncovered new therapeutic possibilities.

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